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Jason Houtchens Phones & Addresses

  • Chandler, AZ
  • Maricopa, AZ
  • 15801 48Th St, Phoenix, AZ 85048
  • 1655 University Dr, Tempe, AZ 85281
  • 2123 Kirkland Ln, Tempe, AZ 85281 (480) 966-0903
  • Carlsbad, CA
  • Fairbanks, AK

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Us Patents

Conjugated Nitro Alkene Anticancer Agents Based On Isoprenoid Metabolism

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US Patent:
7977315, Jul 12, 2011
Filed:
Nov 16, 2007
Appl. No.:
11/941914
Inventors:
Seth D. Rose - Tempe AZ, US
Karl J. Okolotowicz - Goleta CA, US
Rosemarie F. Hartman - Tempe AZ, US
Jason Houtchens - Tempe AZ, US
Assignee:
Arizona Biomedical Research Commission - Pheonix AZ
International Classification:
A61P 35/00
A61K 38/04
A61K 38/05
US Classification:
514 193, 514 219, 514 2191
Abstract:
Conjugated nitro alkene compounds hamper or prevent proliferation of cancer cells in cell culture and in cancer patients, which can result in a decrease in tumor size and/or disappearance of the cancer. The compounds may act by interference with cancer cell biochemistry, in which isoprenoid groups such as farnesyl and geranylgeranyl become bonded to various oncogenic proteins such as Ras, RhoA, RhoB, or some other growth-related cellular protein(s).

Conjugated Nitro Alkene Anticancer Agents Based On Isoprenoid Metabolism

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US Patent:
20050026812, Feb 3, 2005
Filed:
Jul 29, 2004
Appl. No.:
10/901082
Inventors:
Seth Rose - Tempe AZ, US
Karl Okolotowicz - Goleta CA, US
Rosemarie Hartman - Tempe AZ, US
Jason Houtchens - Tempe AZ, US
Assignee:
Arizona Disease Control Research Commission - Phoenix AZ
International Classification:
A61K038/00
A61K031/66
C07K014/00
A61K031/04
A61K031/075
US Classification:
514002000, 514712000, 514740000, 514716000, 568044000, 568583000, 568924000, 514357000, 514408000, 514561000, 530300000, 546329000, 548567000
Abstract:
Conjugated nitro alkene compounds hamper or prevent proliferation of cancer cells in cell culture and in cancer patients, which can result in a decrease in tumor size and/or disappearance of the cancer. The compounds may act by interference with cancer cell biochemistry, in which isoprenoid groups such as farnesyl and geranylgeranyl become bonded to various oncogenic proteins such as Ras, RhoA, RhoB, or some other growth-related cellular protein(s).
Jason O Houtchens from Chandler, AZ, age ~46 Get Report